I have been diagnosed with severe ulcerative colitis and also severe psoriasis. Is there any connection? - severe ulcerative colitis
I have never had health problems before and seemed to almost two years, such as psoriasis and colitis, to come together. I have a dermatologist for a while and said, reluctant to disease, without paying. It's part of my body that there is no treatment of psoriasis. Only Resently have had all the tests of two points (20 years) and said I ulcerative colitis. I think the only person who thinks it might be a connection between these two terrible diseases / UN curable. Ideas?
Wednesday, January 6, 2010
Severe Ulcerative Colitis I Have Been Diagnosed With Severe Ulcerative Colitis And Also Severe Psoriasis. Is There Any Connection?
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Yes, there is a connection, and part of the extra-intestinal complications of ulcerative colitis. There are various dermatological manifestations that are used drugs that can lead to the disease or the body's response to treat.
I do not know the specific ethology of psoriasis, but here's a show for my line of text on the skin disease, is associated with UC.
The skin manifestations of ulcerative colitis are common complications of drug treatments. These include allergic rash, photosensitivity, urticaria, and associated with sulfasalazine and mesalamine less frequently. Patients treated with glucocorticoids frequently develop acne can be aesthetically distressing. Other common dermatologic manifestations associated with UC, including erythema nodosum and pyoderma gangrenosum. Erythema nodosum occurs in 2% to 4% of patients with ulcerative colitis. Its activities generally Parallels bowel disease behind. Erythema nodosum may also occur in response to the component of the drug sulfapyridine for sulfasalazine. What usually occurs by one or morePLE tender, raised, erythematous nodular lesions on the extensor surfaces of the lower extremities. If possible, the diagnosis is made clinically without biopsy because the biopsy is associated with an increased tendency to scar formation. Erythema nodosum generally respond to the treatment of UC. Severe or refractory May require systemic corticosteroids or immunosuppressive therapy. Pyoderma gangrenosum is less common than erythema nodosum and occurs in 1% to 2% of patients. Typically associated with the activity of the colitis, but in spite of the current or intestinal illnesses remain inactive. Lesions may be single or multiple and usually on the trunk or extremities, but the face, chest, or sites of trauma, including stoma intravenously and start growing the sites of classical lesions, erythematous pustules or nodules that break, merge and ulcers dig a big sore, tender, with irregular purple edges. Although the look is dramatic, ulcers are sterile. Histopathology pyoderma has the characteristics of a sterile abscess with marked neutrophil infiltration. Pyoderma gangrenosum can be resolved with the treatment of the underlying colitis are. In most cases usually respond to intra-infected injection of topical treatment with glucocorticoids or sodium cromoglycate, mesalazine, corticosteroids, tacrolimus. In severe cases may require corticosteroids, immunosuppressants such as cyclosporine, azathioprine, methotrexate, tacrolimus, dapsone, or infliximab. Other associated symptoms are less common of the skin with the University of California, Sweet's syndrome or acute febrile neutrophilic dermatosis and pyoderma vegetans Hallopeau. The latter has a presentation similar to pyoderma gangrenosum, but also brings the mouth
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